The National Foundation for Cancer Research is proud to feature Dr. Isaac Witz, the 2023 Szent-Györgyi Prize for Progress in Cancer Research winner, in the latest episode of All Things Cancer. His groundbreaking work forever changed how the world understands and treats cancer.
From Bold Ideas to Breakthroughs
Long before “tumor microenvironment” became a standard term in oncology, Dr. Witz recognized that cancer is not just about tumor cells. It is shaped by the body’s surrounding cells, molecules, and systems — what he calls the cancer ecosystem. At a time when most researchers dismissed these ideas as “unimportant,” Dr. Witz followed the evidence and uncovered insights that have transformed cancer treatment.
Patients at the Center
In his discussion with NFCR CEO Dr. Sujuan Ba, Dr. Witz emphasizes the importance of keeping patients at the heart of research. He explains that therapies cannot simply aim to destroy tumors — they must also consider how the body’s own systems sometimes help cancer survive and spread. This shift in perspective has led to the development of new therapies targeting the environment that supports tumors, rather than just the tumors themselves.
Orphan Results and the Future of Discovery
Dr. Witz also raises concern about “orphan results” — significant findings that often get buried in lower-profile journals and overlooked by the broader scientific community. He believes integrating these hidden insights, potentially with the help of artificial intelligence, will be critical to advancing cures. Collaboration across borders and disciplines, he argues, will also play a central role..
A Vision for Tomorrow
Reflecting on decades of scientific discovery, Dr. Witz offers advice to young researchers: focus on making repeatable, valuable discoveries that can ultimately benefit patients. Looking ahead, his vision for the future of cancer treatment is a holistic approach — one that amplifies the body’s natural defenses against cancer while blocking the processes that allow it to thrive.
Dr. Witz’s story is one of persistence, courage, and transformative impact. His work reminds us that progress often comes from those willing to challenge conventional wisdom.
About All Things Cancer
Each episode of All Things Cancer will spotlight the most pressing topics in oncology, from cutting-edge treatments and emerging research to personal stories of resilience and hope. More than just a podcast, it’s a platform for raising awareness, advancing cancer education, and fostering a global community of support and collaboration.
Hosted by NFCR CEO, Sujuan Ba, Ph.D., this compelling series will bring together the entire ecosystem of cancer research—including leading scientists, oncologists, doctors, patient advocates, caregivers, biotech innovators, and survivors—for powerful discussions on the breakthroughs shaping the future of cancer research, treatment, and care.
All Things Cancer is now available on Spotify and Apple Podcasts, with new episodes released biweekly.
Subscribe now to stay up to date on the latest episodes and join the conversation that’s shaping the future of cancer research. Cancer impacts everyone—whether you’re a patient, caregiver, advocate, or researcher, this podcast delivers invaluable insights from those on the frontlines of the fight against it.
